Hi @charlie.brooker,
Thank you for your answer.
Thinking about a real scenario, if your internal temperature is 5-10C lower than external I would expect you would want to keep the windows closed to avoid bringing the warmer external air inside.
This makes sense, but in real scenarios, the users would have to open their windows at some point to evacuate the CO2 (I’m working on projects for which we would like to achieve zero mechanical ventilation, only natural ventilation).
That’s a different topic from my first question, and I read this, which is already a good answer about air quality in my case.
Are you talking about the cooling effect experienced from increased air movement? (eg standing below a ceiling fan)
It is exactly my point: even if you increase the air of 4-6 °C by opening the windows, the comfort that you get from increased air movement could be better for some people than being in a closed room.
I’m pretty confident that E+ (and so Honeybee) does not account for any increased air movement due to window opening, it will only model the heat transfer of warmer air passing into the space from the outside.
So as a conclusion, this answers my question, thank you! 
I think the problems I am facing is about the user behaviour simulation more than the building at this point.