Interior space thermal distribution

hey guys:

I am doing a simulation of the thermal distribution of an interior space of 4 seasons that has some windows and interior walls. From some research, I know that there are several factors to the simulation, like material’s thermal features, radiance, wind, and the air conditioner.
I know the Thermal engine in Honeybee could do the simulation for the building components like windows, walls, and foundations, etc. But I don’t know how to apply this to my case.

Does anyone have this question before? Or does anyone has any idea about how to do this?
It will be appreciated if I can have any hints.